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Wednesday, July 18, 2018

METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY ...
src: dmd.aspetjournals.org

5-Methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT, sometimes called Foxy) is a psychedelic tryptamine and the methoxy derivative of diisopropyltryptamine (DiPT).


Video 5-Methoxy-N,N-diisopropyltryptamine



Pharmacology

The mechanism that produces the purported hallucinogenic and entheogenic effects of 5-MeO-DiPT is thought to result primarily from 5-HT2A receptor agonism, although additional mechanisms of action such as monoamine oxidase inhibition (MAOI) may be involved also. The strongest receptor binding affinity for 5-MeO-DiPT is at the 5-HT1A receptor.

5-MeO-DiPT is neurotoxic in rats.


Maps 5-Methoxy-N,N-diisopropyltryptamine



Overdose

Excessive doses have caused clinical intoxication, characterized by nausea, vomiting, agitation, hypotension, mydriasis, tachycardia and hallucinations, in a number of young adults. Rhabdomyolysis and renal failure occurred in one young man and another one died 3-4 hours after an apparent rectal overdose. At least one death has been attributed to consumption of 5-MeO-DiPT.


METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY ...
src: dmd.aspetjournals.org

Drug prohibition laws

China

As of October 2015 5-MeO-DiPT is a controlled substance in China.

Denmark

Illegal since February 2004.

Germany

Illegal since September 1999.

Greece

Illegal since February 2003.

Japan

Illegal since April 2005.

Singapore

Illegal since early 2006.

Sweden

Sveriges riksdags health ministry Statens folkhälsoinstitut classified 5-MeO-DiPT as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Oct 1, 2004, in their regulation SFS 2004:696 listed as 5-metoxi-N,N-diisopropyltryptamin (5-MeO-DIPT), making it illegal to sell or possess.

USA

On April 4, 2003, the United States DEA added both 5-MeO-DiPT and alpha-methyltryptamine (AMT) to Schedule I of the Controlled Substances Act under "emergency scheduling" procedures. The drugs were officially placed into Schedule I on September 29, 2004. Prior to its prohibition in the U.S., 5-MeO-DiPT was sold online alongside psychoactive analogues such as DiPT, and DPT, neither of which have yet been expressly outlawed.


What Is the Difference between 5-MeO DMT and DMT? Choosing a DMT ...
src: psychedelictimes.com


See also

  • 5-MeO-DiBF
  • 5-MeO-DMT
  • 5-MeO-DPT
  • 5-MeO-AMT
  • 5-MeO-MiPT
  • DMT
  • DPT
  • AMT
  • DIPT
  • MIPT

METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY ...
src: dmd.aspetjournals.org


References


Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions ...
src: pharmrev.aspetjournals.org


External links

  • Official Ruling Placing 5-MeO-DIPT into Schedule I
  • Erowid information on 5-MeO-DIPT.
  • 5-MeO-DIPT entry in TiHKAL o info

Source of the article : Wikipedia

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